Super-low Dose Endotoxin Pre-conditioning Exacerbates Sepsis Mortality

Sepsis mortality varies dramatically in individuals of variable immune conditions, with poorly defined mechanisms. This phenomenon complements the hypothesis that innate immunity may adopt rudimentary memory, as demonstrated in vitro with endotoxin priming and tolerance in cultured monocytes. Howeve...

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Udgivet i:EBioMedicine
Main Authors: Chen, Keqiang, Geng, Shuo, Yuan, Ruoxi, Diao, Na, Upchurch, Zachary, Li, Liwu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445878/
https://ncbi.nlm.nih.gov/pubmed/26029736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.03.001
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