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Polarization of Low-Grade Inflammatory Monocytes Through TRAM-Mediated Up-Regulation of Keap1 by Super-Low Dose Endotoxin

Subclinical endotoxemia [low levels of bacterial endotoxin (LPS) in the blood stream] has been correlated with chronic inflammatory diseases, with less-understood mechanisms. We have previously shown that chronic exposure to super low doses of LPS polarizes monocytes/macrophages to a pro-inflammator...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Rahtes, Allison, Li, Liwu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378438/
https://ncbi.nlm.nih.gov/pubmed/32765513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01478
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