Integrin-α10 dependency identifies RAC and RICTOR as therapeutic targets in high-grade myxofibrosarcoma

Myxofibrosarcoma is a common mesenchymal malignancy with complex genomics and heterogeneous clinical outcomes. Through gene-expression profiling of 64 primary high-grade myxofibrosarcomas, we defined an expression signature associated with clinical outcome. The gene most significantly associated wit...

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書誌詳細
出版年:Cancer Discov
主要な著者: Okada, Tomoyo, Lee, Ann Y., Qin, Li-Xuan, Agaram, Narasimhan, Mimae, Takahiro, Shen, Yawei, O’Connor, Rachael, López-Lago, Miguel A., Craig, Amanda, Miller, Martin L., Agius, Phaedra, Molinelli, Evan, Socci, Nicholas D., Crago, Aimee M., Shima, Fumi, Sander, Chris, Singer, Samuel
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050162/
https://ncbi.nlm.nih.gov/pubmed/27577794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-1481
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