Rb and p53-deficient Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma Require Skp2 for Survival

Myxofibrosarcoma (MFS) and undifferentiated pleomorphic sarcoma (UPS) are highly genetically complex soft tissue sarcomas. Up to 50% of patients develop distant metastases, but current systemic therapies have limited efficacy. MFS and UPS have recently been shown to commonly harbor copy number alter...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Li, George Z., Okada, Tomoyo, Kim, Young-Mi, Agaram, Narasimhan P., Sanchez-Vega, Francisco, Shen, Yawei, Tsubokawa, Norifumi, Rios, Jordan, Martin, Axel S., Dickson, Mark A., Qin, Li-Xuan, Socci, Nicholas D., Singer, Samuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299798/
https://ncbi.nlm.nih.gov/pubmed/32161142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1269
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