SIAH and EGFR, Two RAS Pathway Biomarkers, are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer

BACKGROUND: Metastatic breast cancer exhibits diverse and rapidly evolving intra- and inter-tumor heterogeneity. Patients with similar clinical presentations often display distinct tumor responses to standard of care (SOC) therapies. Genome landscape studies indicate that EGFR/HER2/RAS “pathway” act...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: van Reesema, Lauren L. Siewertsz, Zheleva, Vasilena, Winston, Janet S., Jansen, Rick J., O’Connor, Carolyn F., Isbell, Andrew J., Bian, Minglei, Qin, Rui, Bassett, Patricia T., Hinson, Virginia J., Dorsch, Kimberly A., Kirby, Brad W., Van Sciver, Robert E., Tang-Tan, Angela M., Harden, Elizabeth A., Chang, David Z., Allen, Cynthia A., Perry, Roger R., Hoefer, Richard A., Tang, Amy H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049993/
https://ncbi.nlm.nih.gov/pubmed/27569656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.08.014
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