SIAH and EGFR, Two RAS Pathway Biomarkers, are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer

BACKGROUND: Metastatic breast cancer exhibits diverse and rapidly evolving intra- and inter-tumor heterogeneity. Patients with similar clinical presentations often display distinct tumor responses to standard of care (SOC) therapies. Genome landscape studies indicate that EGFR/HER2/RAS “pathway” act...

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Pubblicato in:EBioMedicine
Autori principali: van Reesema, Lauren L. Siewertsz, Zheleva, Vasilena, Winston, Janet S., Jansen, Rick J., O’Connor, Carolyn F., Isbell, Andrew J., Bian, Minglei, Qin, Rui, Bassett, Patricia T., Hinson, Virginia J., Dorsch, Kimberly A., Kirby, Brad W., Van Sciver, Robert E., Tang-Tan, Angela M., Harden, Elizabeth A., Chang, David Z., Allen, Cynthia A., Perry, Roger R., Hoefer, Richard A., Tang, Amy H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049993/
https://ncbi.nlm.nih.gov/pubmed/27569656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.08.014
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