SIAH and EGFR, Two RAS Pathway Biomarkers, are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer

BACKGROUND: Metastatic breast cancer exhibits diverse and rapidly evolving intra- and inter-tumor heterogeneity. Patients with similar clinical presentations often display distinct tumor responses to standard of care (SOC) therapies. Genome landscape studies indicate that EGFR/HER2/RAS “pathway” act...

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Vydáno v:EBioMedicine
Hlavní autoři: van Reesema, Lauren L. Siewertsz, Zheleva, Vasilena, Winston, Janet S., Jansen, Rick J., O’Connor, Carolyn F., Isbell, Andrew J., Bian, Minglei, Qin, Rui, Bassett, Patricia T., Hinson, Virginia J., Dorsch, Kimberly A., Kirby, Brad W., Van Sciver, Robert E., Tang-Tan, Angela M., Harden, Elizabeth A., Chang, David Z., Allen, Cynthia A., Perry, Roger R., Hoefer, Richard A., Tang, Amy H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049993/
https://ncbi.nlm.nih.gov/pubmed/27569656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.08.014
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