Sickle Cell Trait Increases Red Blood Cell Storage Hemolysis and Post-Transfusion Clearance in Mice

BACKGROUND: Transfusion of blood at the limits of approved storage time is associated with lower red blood cell (RBC) post-transfusion recovery and hemolysis, which increases plasma cell-free hemoglobin and iron, proposed to induce endothelial dysfunction and impair host defense. There is noted vari...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Osei-Hwedieh, David O., Kanias, Tamir, Croix, Claudette St., Jessup, Morgan, Xiong, Zeyu, Sinchar, Derek, Franks, Jonathan, Xu, Qinzi, M. Novelli, Enrico, Sertorio, Jonas T., Potoka, Karin, Binder, Robert J., Basu, Swati, Belanger, Andrea M., Kim-Shapiro, Daniel B., Triulzi, Darrell, Lee, Janet S., Gladwin, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049931/
https://ncbi.nlm.nih.gov/pubmed/27523807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.08.006
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