Sickle Cell Trait Increases Red Blood Cell Storage Hemolysis and Post-Transfusion Clearance in Mice

BACKGROUND: Transfusion of blood at the limits of approved storage time is associated with lower red blood cell (RBC) post-transfusion recovery and hemolysis, which increases plasma cell-free hemoglobin and iron, proposed to induce endothelial dysfunction and impair host defense. There is noted vari...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Osei-Hwedieh, David O., Kanias, Tamir, Croix, Claudette St., Jessup, Morgan, Xiong, Zeyu, Sinchar, Derek, Franks, Jonathan, Xu, Qinzi, M. Novelli, Enrico, Sertorio, Jonas T., Potoka, Karin, Binder, Robert J., Basu, Swati, Belanger, Andrea M., Kim-Shapiro, Daniel B., Triulzi, Darrell, Lee, Janet S., Gladwin, Mark T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049931/
https://ncbi.nlm.nih.gov/pubmed/27523807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.08.006
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