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Hemolysis and cell-free hemoglobin drive an intrinsic mechanism for human disease

Blood transfusion represents the first and most prescribed cell-based therapy; however, clinical safety and efficacy trials are lacking. Clinical cohort studies have suggested that massive transfusion and/or transfusion of aged stored blood may contribute to multiorgan dysfunction in susceptible pat...

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Detalhes bibliográficos
Main Authors: Gladwin, Mark T., Kanias, Tamir, Kim-Shapiro, Daniel B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314481/
https://ncbi.nlm.nih.gov/pubmed/22446184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62972
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