Dual Anti-Inflammatory and Anti-Angiogenic Action of miR-15a in Diabetic Retinopathy

Activation of pro-inflammatory and pro-angiogenic pathways in the retina and the bone marrow contributes to pathogenesis of diabetic retinopathy. We identified miR-15a as key regulator of both pro-inflammatory and pro-angiogenic pathways through direct binding and inhibition of the central enzyme in...

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Podrobná bibliografie
Vydáno v:EBioMedicine
Hlavní autoři: Wang, Qi, Navitskaya, Svetlana, Chakravarthy, Harshini, Huang, Chao, Kady, Nermin, Lydic, Todd A., Chen, Y. Eugene, Yin, Ke-Jie, Powell, Folami Lamoke, Martin, Pamela M., Grant, Maria B., Busik, Julia V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049929/
https://ncbi.nlm.nih.gov/pubmed/27531575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.08.013
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