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Pyrophosphate Stimulates Differentiation, Matrix Gene Expression and Alkaline Phosphatase Activity in Osteoblasts

Pyrophosphate is a potent mitogen, capable of stimulating proliferation in multiple cell types, and a critical participant in bone mineralization. Pyrophosphate can also affect the resorption rate and bioactivity of orthopedic ceramics. The present study investigated whether calcium pyrophosphate af...

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Publicado en:PLoS One
Main Authors: Pujari-Palmer, Michael, Pujari-Palmer, Shiuli, Lu, Xi, Lind, Thomas, Melhus, Håkan, Engstrand, Thomas, Karlsson-Ott, Marjam, Engqvist, Hakan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049792/
https://ncbi.nlm.nih.gov/pubmed/27701417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163530
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