Pyrophosphate Stimulates Differentiation, Matrix Gene Expression and Alkaline Phosphatase Activity in Osteoblasts

Pyrophosphate is a potent mitogen, capable of stimulating proliferation in multiple cell types, and a critical participant in bone mineralization. Pyrophosphate can also affect the resorption rate and bioactivity of orthopedic ceramics. The present study investigated whether calcium pyrophosphate af...

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Bibliographic Details
Published in:PLoS One
Main Authors: Pujari-Palmer, Michael, Pujari-Palmer, Shiuli, Lu, Xi, Lind, Thomas, Melhus, Håkan, Engstrand, Thomas, Karlsson-Ott, Marjam, Engqvist, Hakan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049792/
https://ncbi.nlm.nih.gov/pubmed/27701417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163530
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