The distribution of BRAF gene fusions in solid tumors and response to targeted therapy

Although the BRAF V600E base substitution is an approved target for the BRAF inhibitors in melanoma, BRAF gene fusions have not been investigated as anticancer drug targets. In our study, a wide variety of tumors underwent comprehensive genomic profiling for hundreds of known cancer genes using the...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Int J Cancer
Hoofdauteurs: Ross, Jeffrey S., Wang, Kai, Chmielecki, Juliann, Gay, Laurie, Johnson, Adrienne, Chudnovsky, Jacob, Yelensky, Roman, Lipson, Doron, Ali, Siraj M, Elvin, Julia A., Vergilio, Jo‐Anne, Roels, Steven, Miller, Vincent A, Nakamura, Brooke N., Gray, Adam, Wong, Michael K, Stephens, Philip J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
Onderwerpen:
Cancer Genetics and Epigenetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049644/
https://ncbi.nlm.nih.gov/pubmed/26314551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29825
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items