The distribution of BRAF gene fusions in solid tumors and response to targeted therapy

Although the BRAF V600E base substitution is an approved target for the BRAF inhibitors in melanoma, BRAF gene fusions have not been investigated as anticancer drug targets. In our study, a wide variety of tumors underwent comprehensive genomic profiling for hundreds of known cancer genes using the...

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Foilsithe in:Int J Cancer
Main Authors: Ross, Jeffrey S., Wang, Kai, Chmielecki, Juliann, Gay, Laurie, Johnson, Adrienne, Chudnovsky, Jacob, Yelensky, Roman, Lipson, Doron, Ali, Siraj M, Elvin, Julia A., Vergilio, Jo‐Anne, Roels, Steven, Miller, Vincent A, Nakamura, Brooke N., Gray, Adam, Wong, Michael K, Stephens, Philip J
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Cancer Genetics and Epigenetics
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049644/
https://ncbi.nlm.nih.gov/pubmed/26314551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29825
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