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Endogenous miRNA and Target Concentrations Determine Susceptibility to Potential ceRNA Competition
Target competition (ceRNA crosstalk) within miRNA-regulated gene networks has been proposed to influence biological systems. To assess target competition, we characterize and quantitate miRNA networks in two cell types. Argonaute iCLIP reveals that hierarchical binding of high- to low-affinity miRNA...
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| Udgivet i: | Mol Cell |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048918/ https://ncbi.nlm.nih.gov/pubmed/25449132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.09.018 |
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