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Endogenous miRNA and Target Concentrations Determine Susceptibility to Potential ceRNA Competition
Target competition (ceRNA crosstalk) within miRNA-regulated gene networks has been proposed to influence biological systems. To assess target competition, we characterize and quantitate miRNA networks in two cell types. Argonaute iCLIP reveals that hierarchical binding of high- to low-affinity miRNA...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048918/ https://ncbi.nlm.nih.gov/pubmed/25449132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.09.018 |
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