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Foxd3 promotes exit from naïve pluripotency through enhancer decommissioning and inhibits germline specification
Following implantation, mouse epiblast cells transit from a naïve to a primed state in which they are competent for both somatic and primordial germ cell (PGC) specification. Using mouse embryonic stem cells (mESC) as an in vitro model to study the transcriptional regulatory principles orchestrating...
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| Опубликовано в: : | Cell Stem Cell |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048917/ https://ncbi.nlm.nih.gov/pubmed/26748758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.09.010 |
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