Minimal Residual Disease Detection and Evolved IGH Clones Analysis in Acute B Lymphoblastic Leukemia Using IGH Deep Sequencing

Acute B lymphoblastic leukemia (B-ALL) is one of the most common types of childhood cancer worldwide and chemotherapy is the main treatment approach. Despite good response rates to chemotherapy regiments, many patients eventually relapse and minimal residual disease (MRD) is the leading risk factor...

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Библиографические подробности
Опубликовано в: :Front Immunol
Главные авторы: Wu, Jinghua, Jia, Shan, Wang, Changxi, Zhang, Wei, Liu, Sixi, Zeng, Xiaojing, Mai, Huirong, Yuan, Xiuli, Du, Yuanping, Wang, Xiaodong, Hong, Xueyu, Li, Xuemei, Wen, Feiqiu, Xu, Xun, Pan, Jianhua, Li, Changgang, Liu, Xiao
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2016
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048610/
https://ncbi.nlm.nih.gov/pubmed/27757113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00403
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