Minimal Residual Disease Detection and Evolved IGH Clones Analysis in Acute B Lymphoblastic Leukemia Using IGH Deep Sequencing

Acute B lymphoblastic leukemia (B-ALL) is one of the most common types of childhood cancer worldwide and chemotherapy is the main treatment approach. Despite good response rates to chemotherapy regiments, many patients eventually relapse and minimal residual disease (MRD) is the leading risk factor...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wu, Jinghua, Jia, Shan, Wang, Changxi, Zhang, Wei, Liu, Sixi, Zeng, Xiaojing, Mai, Huirong, Yuan, Xiuli, Du, Yuanping, Wang, Xiaodong, Hong, Xueyu, Li, Xuemei, Wen, Feiqiu, Xu, Xun, Pan, Jianhua, Li, Changgang, Liu, Xiao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048610/
https://ncbi.nlm.nih.gov/pubmed/27757113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00403
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