Llwytho...
A20 suppresses canonical Smad-dependent fibroblast activation: novel function for an endogenous inflammatory modulator
BACKGROUND: The ubiquitin-editing cytosolic enzyme A20, the major negative regulator of toll-like receptor (TLR)-mediated cellular inflammatory responses, has tight genetic linkage with systemic sclerosis (SSc). Because recent studies implicate endogenous ligand-driven TLR signaling in SSc pathogene...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Arthritis Res Ther |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
BioMed Central
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048449/ https://ncbi.nlm.nih.gov/pubmed/27716397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1118-7 |
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