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Exome sequencing in the knockin mice generated using the CRISPR/Cas system

Knockin (KI) mouse carrying a point mutation has been an invaluable tool for disease modeling and analysis. Genome editing technologies using the CRISPR/Cas system has emerged as an alternative way to create KI mice. However, if the mice carry nucleotide insertions and/or deletions (InDels) in other...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakajima, Kazuo, Kazuno, An-a, Kelsoe, John, Nakanishi, Moe, Takumi, Toru, Kato, Tadafumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048150/
https://ncbi.nlm.nih.gov/pubmed/27698470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34703
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