The Oncoprotein BRD4-NUT Generates Aberrant Histone Modification Patterns

Defects in chromatin proteins frequently manifest in diseases. A striking case of a chromatin-centric disease is NUT-midline carcinoma (NMC), which is characterized by expression of NUT as a fusion partner most frequently with BRD4. ChIP-sequencing studies from NMC patients revealed that BRD4-NUT (B...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Zee, Barry M., Dibona, Amy B., Alekseyenko, Artyom A., French, Christopher A., Kuroda, Mitzi I.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047744/
https://ncbi.nlm.nih.gov/pubmed/27698495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163820
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker