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The Oncoprotein BRD4-NUT Generates Aberrant Histone Modification Patterns
Defects in chromatin proteins frequently manifest in diseases. A striking case of a chromatin-centric disease is NUT-midline carcinoma (NMC), which is characterized by expression of NUT as a fusion partner most frequently with BRD4. ChIP-sequencing studies from NMC patients revealed that BRD4-NUT (B...
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| Wydane w: | PLoS One |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5047744/ https://ncbi.nlm.nih.gov/pubmed/27698495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163820 |
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