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Transcriptional Regulation of Frizzled-1 in Human Osteoblasts by Sp1

The wingless pathway has a powerful influence on bone metabolism and is a therapeutic target in skeletal disorders. Wingless signaling is mediated in part through the Frizzled (FZD) receptor family. FZD transcriptional regulation is poorly understood. Herein we tested the hypothesis that Sp1 plays a...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Yu, Shibing, Yerges-Armstrong, Laura M., Chu, Yanxia, Zmuda, Joseph M., Zhang, Yingze
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047477/
https://ncbi.nlm.nih.gov/pubmed/27695039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163277
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