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Transcriptional Regulation of Frizzled-1 in Human Osteoblasts by Sp1

The wingless pathway has a powerful influence on bone metabolism and is a therapeutic target in skeletal disorders. Wingless signaling is mediated in part through the Frizzled (FZD) receptor family. FZD transcriptional regulation is poorly understood. Herein we tested the hypothesis that Sp1 plays a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yu, Shibing, Yerges-Armstrong, Laura M., Chu, Yanxia, Zmuda, Joseph M., Zhang, Yingze
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047477/
https://ncbi.nlm.nih.gov/pubmed/27695039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163277
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