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Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny.

The random addition of "N nucleotides" by terminal deoxynucleotidyltransferase (TdT) is an important component of the diversity of T-cell receptor genes. We have investigated the expression of TdT during thymocyte differentiation and thymus ontogeny. TdT gene transcripts are confined to im...

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Bibliografiske detaljer
Main Authors: Bogue, M, Gilfillan, S, Benoist, C, Mathis, D
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC50473/
https://ncbi.nlm.nih.gov/pubmed/1438306
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