Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny.

The random addition of "N nucleotides" by terminal deoxynucleotidyltransferase (TdT) is an important component of the diversity of T-cell receptor genes. We have investigated the expression of TdT during thymocyte differentiation and thymus ontogeny. TdT gene transcripts are confined to immature thy...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Bogue, M, Gilfillan, S, Benoist, C, Mathis, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50473/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438306/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.11011
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