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Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells

To prevent rereplication of genomic segments, the eukaryotic cell cycle is divided into two nonoverlapping phases. During late mitosis and G1 replication origins are “licensed” by loading MCM2-7 double hexamers and during S phase licensed replication origins activate to initiate bidirectional replic...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Moreno, Alberto, Carrington, Jamie T., Albergante, Luca, Al Mamun, Mohammed, Haagensen, Emma J., Komseli, Eirini-Stavroula, Gorgoulis, Vassilis G., Newman, Timothy J., Blow, J. Julian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047195/
https://ncbi.nlm.nih.gov/pubmed/27516545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603252113
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