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Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells
To prevent rereplication of genomic segments, the eukaryotic cell cycle is divided into two nonoverlapping phases. During late mitosis and G1 replication origins are “licensed” by loading MCM2-7 double hexamers and during S phase licensed replication origins activate to initiate bidirectional replic...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5047195/ https://ncbi.nlm.nih.gov/pubmed/27516545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603252113 |
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