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Inevitability and containment of replication errors for eukaryotic genome lengths spanning megabase to gigabase

The replication of DNA is initiated at particular sites on the genome called replication origins (ROs). Understanding the constraints that regulate the distribution of ROs across different organisms is fundamental for quantifying the degree of replication errors and their downstream consequences. Us...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Al Mamun, Mohammed, Albergante, Luca, Moreno, Alberto, Carrington, James T., Blow, J. Julian, Newman, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047159/
https://ncbi.nlm.nih.gov/pubmed/27630194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603241113
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