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Inevitability and containment of replication errors for eukaryotic genome lengths spanning megabase to gigabase

The replication of DNA is initiated at particular sites on the genome called replication origins (ROs). Understanding the constraints that regulate the distribution of ROs across different organisms is fundamental for quantifying the degree of replication errors and their downstream consequences. Us...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Al Mamun, Mohammed, Albergante, Luca, Moreno, Alberto, Carrington, James T., Blow, J. Julian, Newman, Timothy J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047159/
https://ncbi.nlm.nih.gov/pubmed/27630194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603241113
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