Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clusters

Iron–sulfur (Fe-S) proteins are thought to play an important role in cancer cells mediating redox reactions, DNA replication, and telomere maintenance. Nutrient-deprivation autophagy factor-1 (NAF-1) is a 2Fe-2S protein associated with the progression of multiple cancer types. It is unique among Fe-...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Darash-Yahana, Merav, Pozniak, Yair, Lu, Mingyang, Sohn, Yang-Sung, Karmi, Ola, Tamir, Sagi, Bai, Fang, Song, Luhua, Jennings, Patricia A., Pikarsky, Eli, Geiger, Tamar, Onuchic, José N., Mittler, Ron, Nechushtai, Rachel
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2016
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047192/
https://ncbi.nlm.nih.gov/pubmed/27621439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612736113
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