Correlation of an epigenetic mitotic clock with cancer risk

BACKGROUND: Variation in cancer risk among somatic tissues has been attributed to variations in the underlying rate of stem cell division. For a given tissue type, variable cancer risk between individuals is thought to be influenced by extrinsic factors which modulate this rate of stem cell division...

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Dettagli Bibliografici
Pubblicato in:Genome Biol
Autori principali: Yang, Zhen, Wong, Andrew, Kuh, Diana, Paul, Dirk S., Rakyan, Vardhman K., Leslie, R. David, Zheng, Shijie C., Widschwendter, Martin, Beck, Stephan, Teschendorff, Andrew E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046977/
https://ncbi.nlm.nih.gov/pubmed/27716309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1064-3
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