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The multi-omic landscape of transcription factor inactivation in cancer
BACKGROUND: Hypermethylation of transcription factor promoters bivalently marked in stem cells is a cancer hallmark. However, the biological significance of this observation for carcinogenesis is unclear given that most of these transcription factors are not expressed in any given normal tissue. MET...
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| Gepubliceerd in: | Genome Med |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4997779/ https://ncbi.nlm.nih.gov/pubmed/27562343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0342-8 |
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