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The multi-omic landscape of transcription factor inactivation in cancer

BACKGROUND: Hypermethylation of transcription factor promoters bivalently marked in stem cells is a cancer hallmark. However, the biological significance of this observation for carcinogenesis is unclear given that most of these transcription factors are not expressed in any given normal tissue. MET...

詳細記述

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書誌詳細
出版年:Genome Med
主要な著者: Teschendorff, Andrew E., Zheng, Shijie C., Feber, Andy, Yang, Zhen, Beck, Stephan, Widschwendter, Martin
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997779/
https://ncbi.nlm.nih.gov/pubmed/27562343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0342-8
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