The multi-omic landscape of transcription factor inactivation in cancer

BACKGROUND: Hypermethylation of transcription factor promoters bivalently marked in stem cells is a cancer hallmark. However, the biological significance of this observation for carcinogenesis is unclear given that most of these transcription factors are not expressed in any given normal tissue. MET...

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Detaylı Bibliyografya
Yayımlandı:Genome Med
Asıl Yazarlar: Teschendorff, Andrew E., Zheng, Shijie C., Feber, Andy, Yang, Zhen, Beck, Stephan, Widschwendter, Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997779/
https://ncbi.nlm.nih.gov/pubmed/27562343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0342-8
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