The multi-omic landscape of transcription factor inactivation in cancer

BACKGROUND: Hypermethylation of transcription factor promoters bivalently marked in stem cells is a cancer hallmark. However, the biological significance of this observation for carcinogenesis is unclear given that most of these transcription factors are not expressed in any given normal tissue. MET...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Genome Med
Main Authors: Teschendorff, Andrew E., Zheng, Shijie C., Feber, Andy, Yang, Zhen, Beck, Stephan, Widschwendter, Martin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997779/
https://ncbi.nlm.nih.gov/pubmed/27562343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0342-8
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki