Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPα as a common target of TRIB1 and PML/RARA

The PML/RARA fusion protein occurs as a result of the t(15;17) translocation in the acute promyelocytic leukemia subtype of human acute myeloid leukemia. Gain of chromosome 8 is the most common chromosomal gain in human acute myeloid leukemia, including acute promyelocytic leukemia. We previously de...

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Veröffentlicht in:Haematologica
Hauptverfasser: Keeshan, Karen, Vieugué, Pauline, Chaudhury, Shahzya, Rishi, Loveena, Gaillard, Coline, Liang, Lu, Garcia, Elaine, Nakamura, Takuro, Omidvar, Nader, Kogan, Scott C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2016
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046652/
https://ncbi.nlm.nih.gov/pubmed/27390356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.138503
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