Interplay between transglutaminases and heparan sulphate in progressive renal scarring

Transglutaminase-2 (TG2) is a new anti-fibrotic target for chronic kidney disease, for its role in altering the extracellular homeostatic balance leading to excessive build-up of matrix in kidney. However, there is no confirmation that TG2 is the only transglutaminase involved, neither there are str...

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Udgivet i:Sci Rep
Main Authors: Burhan, Izhar, Furini, Giulia, Lortat-Jacob, Hugues, Atobatele, Adeola G., Scarpellini, Alessandra, Schroeder, Nina, Atkinson, John, Maamra, Mabrouka, Nutter, Faith H., Watson, Philip, Vinciguerra, Manlio, Johnson, Timothy S., Verderio, Elisabetta A. M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046136/
https://ncbi.nlm.nih.gov/pubmed/27694984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31343
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