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CRISPR/Cas9 Targets Chicken Embryonic Somatic Cells In Vitro and In Vivo and generates Phenotypic Abnormalities

Chickens are an invaluable model for studying human diseases, physiology and especially development, but have lagged in genetic applications. With the advent of Programmable Engineered Nucleases, genetic manipulation has become efficient, specific and rapid. Here, we show that the CRISPR/Cas9 system...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Abu-Bonsrah, Kwaku Dad, Zhang, Dongcheng, Newgreen, Donald F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046125/
https://ncbi.nlm.nih.gov/pubmed/27694906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34524
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