Simultaneous induction of apoptosis and necroptosis by Tanshinone IIA in human hepatocellular carcinoma HepG2 cells

Tanshinone IIA (Tan IIA), a constituent of the traditional medicinal plant Salvia miltiorrhiza BUNGE, has been reported to possess anticancer activity through induction of apoptosis in many cancer cells. Surprisingly, the present study finds that Tan IIA simultaneously causes apoptosis and necroptos...

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Udgivet i:Cell Death Discov
Main Authors: Lin, C-Y, Chang, T-W, Hsieh, W-H, Hung, M-C, Lin, I-H, Lai, S-C, Tzeng, Y-J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045965/
https://ncbi.nlm.nih.gov/pubmed/27752362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.65
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