Tanshinone IIA Downregulates Lipogenic Gene Expression and Attenuates Lipid Accumulation through the Modulation of LXRα/SREBP1 Pathway in HepG2 Cells

Abnormal and excessive accumulation of lipid droplets within hepatic cells is the main feature of steatosis and nonalcoholic fatty liver disease (NAFLD) or metabolic-associated fatty liver disease (MAFLD). Dysregulation of lipogenesis contributes to hepatic steatosis and plays an essential role in t...

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I publikationen:Biomedicines
Huvudupphovsmän: Gao, Wan-Yun, Chen, Pei-Yi, Hsu, Hao-Jen, Lin, Ching-Yen, Wu, Ming-Jiuan, Yen, Jui-Hung
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004631/
https://ncbi.nlm.nih.gov/pubmed/33806955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9030326
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