Simultaneous induction of apoptosis and necroptosis by Tanshinone IIA in human hepatocellular carcinoma HepG2 cells

Tanshinone IIA (Tan IIA), a constituent of the traditional medicinal plant Salvia miltiorrhiza BUNGE, has been reported to possess anticancer activity through induction of apoptosis in many cancer cells. Surprisingly, the present study finds that Tan IIA simultaneously causes apoptosis and necroptos...

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Pubblicato in:Cell Death Discov
Autori principali: Lin, C-Y, Chang, T-W, Hsieh, W-H, Hung, M-C, Lin, I-H, Lai, S-C, Tzeng, Y-J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045965/
https://ncbi.nlm.nih.gov/pubmed/27752362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.65
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