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CDR3 motif generation and selection in the BV19-utilizing subset of the human CD8 T cell repertoire

The amino acids at the V - J rearrangement junction of TCR are encoded by the D region, and by N or P nucleotides. Together they comprise the NDN region, the specific pMHC selection surface of the TCR β-chain. As an extension of our earlier work on the recall response to influenza M1(58-66) in HLA-A...

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Publicat a:Mol Immunol
Autors principals: Yassai, Maryam B., Demos, Wendy, Gorski, Jack
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045866/
https://ncbi.nlm.nih.gov/pubmed/26963408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2016.02.014
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