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The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways

BACKGROUND: The formation of new lymphatic vessels provides an additional route for tumour cells to metastasize. Therefore, inhibiting lymphangiogenesis represents an interesting target in cancer therapy. First evidence suggests that histone deacetylase inhibitors (HDACi) may mediate part of their a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:BMC Cancer
मुख्य लेखकों: Hrgovic, Igor, Doll, Monika, Kleemann, Johannes, Wang, Xiao-Fan, Zoeller, Nadja, Pinter, Andreas, Kippenberger, Stefan, Kaufmann, Roland, Meissner, Markus
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045659/
https://ncbi.nlm.nih.gov/pubmed/27716272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2807-y
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