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Dimethylfumarate Inhibits Colorectal Carcinoma Cell Proliferation: Evidence for Cell Cycle Arrest, Apoptosis and Autophagy

Recent studies have proven that Dimethylfumarate (DMF) has a marked anti-proliferative impact on diverse cancer entities e.g., on malignant melanoma. To explore its anti-tumorigenic potential, we examined the effects of DMF on human colon carcinoma cell lines and the underlying mechanisms of action....

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Kaluzki, Irina, Hailemariam-Jahn, Tsige, Doll, Monika, Kaufmann, Roland, Balermpas, Panagiotis, Zöller, Nadja, Kippenberger, Stefan, Meissner, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912700/
https://ncbi.nlm.nih.gov/pubmed/31661890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111329
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