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A Sex-Dependent, Tropic Role for Leptin in the Somatotrope as a Regulator of POU1F1 and POU1F1-Dependent Hormones

Pituitary somatotropes perform the key function of coordinating organismic growth and body composition with metabolic signals. However, the mechanism by which they sense and respond to metabolic signals via the adipokine leptin is unknown. The complex interplay between the heterogeneous cell types o...

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Détails bibliographiques
Publié dans:Endocrinology
Auteurs principaux: Odle, Angela K., Allensworth-James, Melody L., Akhter, Noor, Syed, Mohsin, Haney, Anessa C., MacNicol, Melanie, MacNicol, Angus M., Childs, Gwen V.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045503/
https://ncbi.nlm.nih.gov/pubmed/27571135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1472
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