Wip1 suppresses ovarian cancer metastasis through the ATM/AKT/Snail mediated signaling

Inactivation of p53 greatly contributes to serous ovarian cancer, while the role of the wild-type p53 induced phosphatase 1 (Wip1) is quite unclear. In this study, by silencing or overexpression of Wip1, we found that Wip1 suppressed ovarian cancer cell invasion, migration, epithelial to mesenchymal...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yin, Sheng, Wang, Pan, Yang, Lina, Liu, Yang, Wang, Yan, Liu, Mingming, Qi, Zihao, Meng, Jiao, Shi, Ting-Yan, Yang, Gong, Zang, Rongyu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045401/
https://ncbi.nlm.nih.gov/pubmed/27121065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8833
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