SOCS-1 rescues IL-1β-mediated suppression of epithelial sodium channel in mouse lung epithelial cells via ASK-1

BACKGROUND: Acute lung injury (ALI) is characterized by alveolar damage, increased levels of pro-inflammatory cytokines and impaired alveolar fluid clearance. Recently, we showed that the deletion of Apoptosis signal-regulating kinase 1 (ASK1) protects against hyperoxia-induced acute lung injury (HA...

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Опубликовано в: :Oncotarget
Главные авторы: Galam, Lakshmi, Soundararajan, Ramani, Breitzig, Mason, Rajan, Ashna, Yeruva, Rajashekar Reddy, Czachor, Alexander, Harris, Francine, Lockey, Richard F, Kolliputi, Narasaiah
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045379/
https://ncbi.nlm.nih.gov/pubmed/27058411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8543
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