Targeted drug delivery to ischemic stroke via chlorotoxin-anchored, lexiscan-loaded nanoparticles

Ischemic stroke is a leading cause of disability and death worldwide. Current drug treatment for stroke remains inadequate due to the existence of the blood-brain barrier. We proposed an innovative nanotechnology-based autocatalytic targeting approach, in which the blood-brain barrier modulator lexi...

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Bibliographische Detailangaben
Veröffentlicht in:Nanomedicine
Hauptverfasser: Han, Liang, Cai, Qiang, Tian, Daofeng, Kong, Derek K., Gou, Xingchun, Chen, Zeming, Strittmatter, Stephen M., Wang, Zuoheng, Sheth, Kevin N., Zhou, Jiangbing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045320/
https://ncbi.nlm.nih.gov/pubmed/27039220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2016.03.005
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