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Targeted drug delivery to ischemic stroke via chlorotoxin-anchored, lexiscan-loaded nanoparticles

Ischemic stroke is a leading cause of disability and death worldwide. Current drug treatment for stroke remains inadequate due to the existence of the blood-brain barrier. We proposed an innovative nanotechnology-based autocatalytic targeting approach, in which the blood-brain barrier modulator lexi...

詳細記述

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書誌詳細
出版年:Nanomedicine
主要な著者: Han, Liang, Cai, Qiang, Tian, Daofeng, Kong, Derek K., Gou, Xingchun, Chen, Zeming, Strittmatter, Stephen M., Wang, Zuoheng, Sheth, Kevin N., Zhou, Jiangbing
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045320/
https://ncbi.nlm.nih.gov/pubmed/27039220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2016.03.005
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