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Blunted cardiac response to hemorrhage in cirrhotic rats is mediated by local macrophage-released endocannabinoids

BACKGROUND & AIMS: Cirrhosis is associated with blunted cardiovascular response to stimuli such as hemorrhage, but the mechanism remains unclear. We aimed to clarify the role of endocannabinoids in blunted hemorrhage response in cirrhotic rats. METHODS: Cirrhosis was induced by bile duct ligatio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Hepatol
Hauptverfasser: Gaskari, Seyed Ali, Liu, Hongqun, D’Mello, Charlotte, Kunos, George, Lee, Samuel S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045259/
https://ncbi.nlm.nih.gov/pubmed/25640062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.01.021
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