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Blunted cardiac response to hemorrhage in cirrhotic rats is mediated by local macrophage-released endocannabinoids

BACKGROUND & AIMS: Cirrhosis is associated with blunted cardiovascular response to stimuli such as hemorrhage, but the mechanism remains unclear. We aimed to clarify the role of endocannabinoids in blunted hemorrhage response in cirrhotic rats. METHODS: Cirrhosis was induced by bile duct ligatio...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Gaskari, Seyed Ali, Liu, Hongqun, D’Mello, Charlotte, Kunos, George, Lee, Samuel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045259/
https://ncbi.nlm.nih.gov/pubmed/25640062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.01.021
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