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Mechanisms of TNFα-induced cardiac dysfunction in cholestatic bile duct-ligated mice: Interaction between TNFα and endocannabinoids

BACKGROUND & AIMS: Chronic liver disease is associated with endotoxemia, oxidative stress, increased endocannabinoids and decreased cardiac responsiveness. Endocannabinoids activate the tumor necrosis factor-alpha (TNFα)–nuclear factor κB (NFκB) pathway. However, how they interact with each othe...

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Detalhes bibliográficos
Main Authors: Yang, Ying-Ying, Liu, Hongqun, Nam, Soon Woo, Kunos, George, Lee, Samuel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958049/
https://ncbi.nlm.nih.gov/pubmed/20626112
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