A synthetic three-dimensional niche system facilitates generation of functional hematopoietic cells from human-induced pluripotent stem cells

BACKGROUND: The efficient generation of hematopoietic stem cells (HSCs) from human-induced pluripotent stem cells (iPSCs) holds great promise in personalized transplantation therapies. However, the derivation of functional and transplantable HSCs from iPSCs has had very limited success thus far. MET...

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Gepubliceerd in:J Hematol Oncol
Hoofdauteurs: Xu, Yulin, Shan, Wei, Li, Xia, Wang, Binsheng, Liu, Senquan, Wang, Yebo, Long, Yan, Tie, Ruxiu, Wang, Limengmeng, Cai, Shuyang, Zhang, Hao, Lin, Yu, Zhang, Mingming, Zheng, Weiyan, Luo, Yi, Yu, Xiaohong, Yee, Jiing-Kuan, Ji, Junfeng, Huang, He
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043527/
https://ncbi.nlm.nih.gov/pubmed/27686241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0326-6
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