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Interleukin-6 signaling regulates hematopoietic stem cell emergence

Hematopoietic stem cells (HSCs) produce all lineages of mature blood cells for the lifetime of an organism. In vertebrates, HSCs derive from the transition of the hemogenic endothelium (HE) in the floor of the embryonic dorsal aorta. Most recently, a series of proinflammatory factors, such as tumor...

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Bibliographic Details
Published in:Exp Mol Med
Main Authors: Tie, Ruxiu, Li, Honghu, Cai, Shuyang, Liang, Zuyu, Shan, Wei, Wang, Binsheng, Tan, Yamin, Zheng, Weiyan, Huang, He
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813302/
https://ncbi.nlm.nih.gov/pubmed/31649245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0320-5
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